ISSN 1662-4009 (online)

ey0020.13-3 | Section | ESPEYB20

13.3. Evolutionary constraint and innovation across hundreds of placental mammals

MJ Christmas , IM Kaplow , DP Genereux , MX Dong , GM Hughes , X Li

In Brief: The authors of this large international project describe the generation of ‘Zoonomia’, which is a large comparative genomics resource covering 240 different mammalian species. Among their many findings, the authors use this resource to: i) document the vast range of biodiversity on earth, ii) identify 3.6 million genomic sites that are perfectly conserved across species, indicating genes and regulatory regions that are likely essential for mammalian surviva...